Lab Members

Principal Investigator

Dr. Jean Chen
PhD Biomedical Engineering
McGill University
jchen at research dot baycrest dot org

Positions

  • 2011 – present, Director, Neuroimaging Lab at Baycrest
  • 2018 – present, Senior Scientist, Rotman Research Institute, Baycrest
  • 2018 – present, Associate Professor, Medical Biophysics, University of Toronto
  • 2011 – 2018, Scientist, Rotman Research Institute, Baycrest
  • 2011 – 2018, Assistant Professor, Medical Biophysics, University of Toronto

Education

  • 2009 – 2011, Postdoc, Radiology, Massachusetts General Hospital, Harvard Medical School
  • 2005 – 2009, PhD, Biomedical Engineering, McGill University
  • 2002 – 2004, MSc, Electrical Engineering, University of Calgary

Dr. Chen was trained at the Montreal Neurological Institute and the Martinos Center for Biomedical Imaging. Her current research revolves around the theme of novel methodological development for the study of brain physiology in aging and age-related brain diseases. Her specific interests include studying the neurovascular and electrophysiological mechanisms underlying resting-state fMRI.

Jean Chen

 

Current Lab Members

Current Postdoctoral Fellows

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Dr. Seyedmohammad Shams
Postdoctoral Fellow
PhD Bio-electrical Engineering
University of Tehran

Dr. Shams’ research interests lie primarily at the intersection of functional neuroimaging modalities (especially fMRI data and EEG), machine learning algorithms, statistical inferences and the methods of time-frequency analysis. The theme of Dr. Shams’ research is to establish practical algorithms for multi-subject activation detection, identifying functional brain networks, and approximating blood oxygenation level dependent (BOLD) signal response shape from fMRI data. His research has contributed to the development of algorithms that address the problems in functional neuroimaging in a wide range of applications of computational methods to better understand the function of the brain. Over the last 10 years, he has built ample skills in mathematical methods; including statistical pattern recognition and digital image processing besides methods for preprocessing and processing EEG, structural and functional MRI, that are useful for developing new frameworks to investigate the physiological basis and neural mechanism underlying fMRI.

Current Doctoral Students

JordanChad

Jordan Chad
PhD Candidate
MSc Theoretical Physics
University of Toronto

Jordan’s research focuses on using diffusion MRI (dMRI) to model brain microstructure based on the pattern of microscopic diffusion of water molecules through brain tissue. Jordan’s research goal is the comparison, validation and optimization of mathematical models of brain microstructure derived from dMRI, with a special focus on separating out the effect of extracellular free water molecules from the dMRI signal to improve the specificity of these models to processes that occur within brain tissue.

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Zachary Zhong
PhD Candidate
B.Eng Electrical and Biomedical Engineering
McMaster University.

Zachary’s project focus is on analyzing the relationship between electrophysiological signal and BOLD signal.

Current Masters Students

Current Research Staff

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Jacob Matthews
MRI Specialist
MSc Medical Biophysics
University of Western Ontario
jmatthews at research dot baycrest dot org

Jacob Matthews is the MRI Specialist at the Rotman Research Institute, working within Dr. Chen’s research lab. He received both an Honours Bachelor of Medical Science and a Master of Science in Medical Biophysics from the University of Western Ontario. His Master’s research was conducted out of the Robarts Research Institute and the Brain and Mind Institute, involving laminar functional imaging of auditory cortex using fMRI at 7T. His current work includes consulting on MRI experimental design,  acquisition, and analysis, maintaining the ancillary equipment for MRI research, testing and reporting on newly available MRI technology, and acting as a resource person for the wider Rotman community. He also conducts research within Dr. Chen’s lab.

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Annette Weekes
Chief MRI Technologist
aweekes at research dot baycrest dot org

 

Annette Weekes-Holder is the Senior Research MRI Technologist and MRI Safety Officer at the Rotman Research Institute. Annette is licensed with the College of Medical Radiation Technologist of the province of Ontario with an extensive background in Research and Clinical Magnetic Resonance Imaging.

Current Research Assistants

Nick Teller

Nick Teller
Volunteer
BSc Health Sciences
McMaster University

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Lydia Sun
BSc Neuroscience and Statistical Science
University of Toronto
2019

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Ahmad Hussein
Research Assistant
BSc Nanotechnology
University of Waterloo

Ahmad is currently a part-time RA working on investigating the link between HRV, functional connectivity and mood. Previously as a co-op student with the lab, he worked on a project looking into the association between resting-state fMRI and aortic pulse-wave velocity in healthy adults. Ahmad completed his undergraduate degree in Nanotechnology Engineering from the University of Waterloo in 2019.

Current Co-op Students

Jacob Chausse

Jacob Chausse
Co-op Student
Nanotechnology Engineering
University of Waterloo

Jacob is working on programming Monte Carlo models of the fMRI BOLD signal to provide comparisons of modeling techniques and a create versatile modeling tool.

Current Undergraduate Research Students

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Ana Han
Summer Student
Health Sciences
McMaster University

Ana is currently a summer student whose research is on using fixel-based analysis to analyse diffusion MRI data. She is focused on studying the selective degeneration of white matter tracts in aging.

Arjun

Arjun Patel
Summer Student
Biology & PNB
McMaster University

Arjun is currently a summer student studying white matter microstructure in association with cognition. He is focused on studying diffusion MRI and the use of free water (FW) as a biomarker for cognitive and functional decline. 

Hiba Taha

Hiba Taha
Summer Student
Neuroscience
University of Toronto

Hiba is currently a summer CO-OP student studying white matter differences in the healthy aging population. She is also interested in the use of neuroimaging techniques such as Diffusion Kurtosis Imaging (DKI) to assess and understand aging white matter tissue. Hiba is currently completing her undergraduate degree at the University of Toronto in Neuroscience, with minors in Physiology and Immunology.

Current Visiting Students

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Nok Srisaikaew
PhD Candidate
Anatomy
Chiang Mai University

Nok’s research is mainly focused on the early detection of Alzheimer’s disease via a key structure named the “fornix”. Using MRI techniques she aims to establish biological and imaging markers to indicate the progression of the disease. In order to better understand age-related neurological disorders indicated by human brain anatomical changes related to cognitive decline, fresh cadaveric heads were used to study the arterial supply and anatomical of the fornix. As well, diffusion tensor imaging (DTI) was used to measure the microstructure of the fornix in healthy aging and MCI patients, and magnetic resonance spectroscopy (MRS) was used to measure human brain metabolites to find chemical shift patterns indicative of early stage of AD.

Current External Collaborating Students

Current Volunteers

Lab Alumni

Past Postdoctoral Fellows

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Dr. Aras Kayvanrad
Postdoctoral Fellow
PhD Biomedical Engineering
The University of Western Ontario
2017-2019

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Dr. Ali Golestani
Postdoctoral Fellow
PhD Electrical Engineering
University of Calgary
2013-2016

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Dr. Sungho Tak
Postdoctoral Fellow
PhD Biomedical Engineering
Korean Advanced Institute of Science and Technology
2012-2014

Past Doctoral Students

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Zahra Faraji-Dana
PhD Graduate
Medical Biophysics
University of Toronto
Degree Awarded: September 2016

Past Masters Students

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Azin Esmaelbeigi
MSc Graduate
MSc Medical Biophysics
University of Toronto
Degree Awarded: January 2020

Azin is working on quantitative mapping of cerebrovascular reactivity (CVR) using resting state fMRI. She is focusing on healthy elderly to study the effect of age on CVR. She is also interested in looking at the changes in characteristics of physiological hemodynamic response functions during aging. She completed her undergraduate degree at the University of Toronto in Biomedical Physics, minoring in Mathematics. She defended her Masters degree with the Cranium Lab at the end of 2019. 

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Don Ragot
MSc Graduate
Medical Biophysics
University of Toronto
Degree Awarded: March 2018

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Powell Chu
MSc Graduate
Medical Biophysics
University of Toronto
Degree Awarded: August 2016

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Jonathan Kwinta
MSc Graduate
Medical Biophysics
University of Toronto
Degree Awarded: January 2016

Past Undergraduate Thesis Students

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Om Batt
Undergraduate Thesis Student
Engineering Science
University of Toronto
2012

Past Research Staff

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Yasha Khatamian
fMRI Engineer
MEng. Biomedical Engineering
McGill University
2011-2016

Past Research Assistants

Shreyas

Shreyas Harita
Research Assistant
MSc Neuroscience
Queen’s University
2018-2019

Abhay

Abhay Issar
Undergraduate Student, Life Sciences
University of Toronto
2016-2017

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Sheliza Halani
Research Assistant
BSc Electrical Engineering
University of British Columbia
2014

Past Co-op Students

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Paul Chang
Co-op Student
Biomedical Engineering
University of Waterloo
2021

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Jillian Krotz
Co-op Student
Biomedical Engineering
University of Waterloo
2020

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Chironjeev Kanjilal
Co-op student
Physics
University of British Columbia
2017

James

James Ward
Co-op Student
University of British Columbia
2017

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Sarah Dyck
Co-op student
Life Physics
University of Waterloo
2017

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David Lin
Co-op student
Nanotechnology Engineering
University of Waterloo
2017

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Emma Langlois
Co-op student
Life Physics
University of Waterloo
2017

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Nicole Yuen
Co-op student
Life Physics (Hon.)
University of Waterloo
2016

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Lucy Wei
Co-op student
Biophysics (Hon.)
University of British Columbia
2015

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Nathaniel Osachoff
Co-op student
Engineering Physics
University of British Columbia
2015

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Kathy Xu
Co-op student
Electrical Engineering
University of British Columbia
2013

Past Undergraduate Research Students

Jigar Lad

Jigar Lad
Summer Student
B.Sc. Medical Physics
McMaster University
2020

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Megan Scarlett
Summer Web Dev Staff
Dalhousie University
2018

William Kim Don

William Kim
Summer Student
Physics
Queen’s University
2017

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Josephine Tan
Summer Student
Biological and Medical Physics
University of Guelph
2017

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Barry Fung
Undergraduate Researcher
Engineering Science
University of Toronto
2014

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Lily Lau
Undergraduate Researcher
Engineering Science
University of Toronto
2013

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Tim Liu
Undergraduate Researcher
Engineering Science
University of Toronto
2012

Past External Collaborating Students

Jean Hautier

Jean Hautier
Foreign Collaborator
Mathematics and Modelisation
2020

Past Volunteers

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Amy Lin
Volunteer
BSc Biochemistry and Neuroscience
University of Toronto
alin at research dot baycrest dot org

Dan

Dan Tran
Undergraduate Student, Neuroscience
McGill University
2017