Research Focus

Dr. Strother received BSc and MSc degrees in physics and mathematics from Auckland University in his native New Zealand. With the help of a Rotary International Fellowship he completed a PhD in Electrical Engineering from McGill University, Montreal (1986) in Positron Emission Tomography (PET) research performed at the Montreal Neurological Institute. After a fellowship in neurological PET at Memorial Sloan Kettering Cancer Center, New York, in 1989 he joined the VA Medical Center, Minneapolis as senior PET Physicist, and Assistant Professor of Radiology at the University of Minnesota where he became Professor of Radiology in 2002. In 2004 he moved to Toronto as a senior scientist at the Rotman Research Institute (RRI), Baycrest, and Professor of Medical Biophysics at the University of Toronto. His research interests include neuro-informatics and high-performance computing for data quality control, curation and analysis of neuroimaging--particularly fMRI/MRI, EEG and PET--and big clinical data sets using statistical and machine-learning techniques. He has leadership roles in Brain-CODE (https://www.braincode.ca/) developing and managing the neuroimaging data repository, and is on the executives of the multi-site neurodegeneration (https://ondri.ca/) and depression (https://www.canbind.ca/) research programs funded by the Ontario Brain Institute. Nationally and internationally he is a senior investigator in the Canadian Open Neuroscience Platform, and a Canadian representative on the Council for Training, Science and Infrastructure at the Neuroscience standards organisation, the International Neuroinformatics Coordinating Facility (https://www.incf.org/), based in Stockholm, Sweden. He is a past member of the Neuro-technology Review Committee, at the National Institutes of Health (NIH), USA, and past chairman of the international Neuroinformatics Standards Committee, NIH, that produced the NIfTI neuroimaging format standard. He is also a cofounder of ADMdx, Inc. in Chicago, a medical analysis and diagnostics company.

Select Publications

• Freedman M, Leach L, Carmela Tartaglia M, Stokes KA, Goldberg Y, Spring R, Nourhaghighi N, Gee T, Strother SC, Alhaj MO, Borrie M, Darvesh S, Fernandez A, Fischer CE, Fogarty J, Greenberg BD, Gyenes M, Herrmann N, Keren R, Kirstein J, Kumar S, Lam B, Lena S, McAndrews MP, Naglie G, Partridge R, Rajji TK, Reichmann W, Uri Wolf M, Verhoeff NPLG, Waserman JL, Black SE, Tang-Wai DF. (2018). The Toronto Cognitive Assessment (TorCA): normative data and validation to detect amnestic mild cognitive impairment.. Alzheimer's research & therapy, 10, 65.
• Churchill NW, Spring R, Afshin-Pour B, Dong F, Strother SC. (2015). An Automated, Adaptive Framework for Optimizing Preprocessing Pipelines in Task-Based Functional MRI. PLoS One, 10(7)
• Rasmussen PM, Hansen LK, Madsen KH, Churchill N, Strother SC. (2012). Model sparsity and brain pattern interpretation of classification models in neuroimaging. Pattern Recognition, 45(6), 2085-2100.
• Fishman KN, Roberts AC, Orange JB, Sunderland KM, Marras C, Tan B, Steeves T, Kwan D, Lang AE, Grimes D, Levine B, Masellis M, Binns MA, Jog M, Strother SC, the ONDRI Investigators, McLaughlin PM, Troyer AK. (2021). Bilingualism in Parkinson’s disease: Help or hindrance to cognition and quality of life?. Journal of the International Neuropsychological Society, 43, 199-212.

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