I am currently pursuing three questions. First, a hallmark feature of mild cognitive impairment (MCI) is that people repeatedly ask the same question or say the same thing, and they do so without any evidence that the question or statement is familiar. Unlike you and I, they do not retract and say "Did I already ask you that?" This suggests that familiarity is impaired in MCI, but the existing evidence is evenly split, with half of the studies showing intact familiarity in MCI, and the other half showing that it is impaired. I am currently developing novel ways to assess familiarity in order to see if it is indeed impaired in MCI. I will then see how these measures of familiarity map on to physiological markers of familiarity - what is that gut sense anyway, and is it impaired in MCI? Second, survivors of childhood trauma can have exquisitely detailed episodic autobiographical memory, even for events occurring in the typical "childhood amnesia" period. Does early life trauma curtail childhood amnesia, and how does it affect autobiographical memory for later, non-traumatic periods in one's life? Finally, there is currently no effective treatment for dementia, so how can we detect it early prevent it? My post-doctoral fellow, Dr. Rachel Rabi, is looking at ERP biomarkers of disinhibition in people with MCI. This work is being done in collaboration with Dr. Claude Alain and Dr. Lynn Hasher. I am also running two clinical trials under the CCNA umbrella (one an exercise and nutrition intervention, and the other a cognitive training and engaging leisure intervention) in efforts to build cognitive reserve and reduce dementia risk.