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Complex Data Analysis
ronaldmb
Posted on 09/17/14 14:30:23
Number of posts: 5
ronaldmb posts:

Hi all,

I am working on a pretty complex dataset and am just wondering if anyone knows whether or not a PLS analysis would be appropriate / could work. The data consists of 2 conditions (rest vs. active), 2 participant groups (control vs feedback), 2 sessions ( 1 vs. 2), 14 participants total (7 per group), 15 frequency bands, and 3160 possible Functional Connections (based on a coherence analysis).

I am just wondering if there is anyway to use a PLS to test differences in Functional connectivity between conditions and groups, across sessions.

I have done a PLS before using a 2 (conditions) x 19 (participants) x 15 (frequency bins) x 3160 neural connections. That one was more straight forward. However I have a feeling that throwing in the groups and sessions makes a PLS not usable. If anyone has any insight or suggestions on how to analyze this data that would be great.
Thanks a lot!

-Ron

Replies:

Untitled Post
rmcintosh
Posted on 09/17/14 16:53:47
Number of posts: 394
rmcintosh replies:

quote:

Hi all,

I am working on a pretty complex dataset and am just wondering if anyone knows whether or not a PLS analysis would be appropriate / could work. The data consists of 2 conditions (rest vs. active), 2 participant groups (control vs feedback), 2 sessions ( 1 vs. 2), 14 participants total (7 per group), 15 frequency bands, and 3160 possible Functional Connections (based on a coherence analysis).

I am just wondering if there is anyway to use a PLS to test differences in Functional connectivity between conditions and groups, across sessions.

I have done a PLS before using a 2 (conditions) x 19 (participants) x 15 (frequency bins) x 3160 neural connections. That one was more straight forward. However I have a feeling that throwing in the groups and sessions makes a PLS not usable. If anyone has any insight or suggestions on how to analyze this data that would be great.
Thanks a lot!

-Ron

Hi Ron - you can certainly use PLS for this, but you may have to run a few analyses to get an idea of what you have.   I might suggest something like:

 

1) run the whole thing to get a feel for the number of stable effects

2) if #1 yields good results, break it down along a reasonable dimension (e.g., group) to see what comes out.  You can think of this as a sort of post-hoc test

3) consider putting in apriori contrasts of interest to evaluate specific effects (non-rotated PLS)

I'd be interested to hear how this goes, so please let me know!

 

cheers

 

Randy




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