Back to PLS Help

Brain score - Behavior correlations for negative saliences

Posted on 11/25/13 13:15:56
Number of posts:
posts:

Hi,

I did a non-rotated PLS analysis. There are 2 tasks, A and B. I obtained a siginificant LV, where positive saliences are regions that were more activavated in task A vs. task B, and negative saliences were more activated in task B vs. A. 
 
When I correlate the brain scores for each subject for task B with each subject's performance on task B, I obtain a significant, positive correlation. I am wondering how this should be interpreted. Does this mean that more activation in negative salience regions was positively or negatively correlated with performance?
 
Thanks,
David
 
 

Replies:

Untitled Post

I'm Online
nlobaugh
Posted on 11/27/13 10:35:35
Number of posts: 229
nlobaugh replies:

brainscores reflect the 'overall' strength of a difference between conditions across the brain.  Presumably, the individuals with high brainscores on taskB generally show the largest A/B differences (i.e.  lower brainscores on taskA)????

If, for example, your behavioural data are RT, then a positive correlation of behaviour with brainscores would indicate that those with the longest RTs have the largest global differences between the conditions.

A better way to address your question might be to run a behavPLS with your data - that will show you where the conditions are similar, and where they are different.

nancy



Untitled Post

Posted on 11/27/13 10:53:16
Number of posts:
replies:

Thanks for the reply.

I've added the actual data below. In this example, there is a significant negative correlation between Brain scores on task B and RT.  I guess what I am confused about is whether the person with the most negative brain score  (subject 12)  has the most or the least difference in activation  between tasks B vs. A .   

Thanks for the help,

David

 

Subject Brain Score RT
1 -21.1581 2641.48
2 -34.84845 2880.925
3 -7.0453 2125.32
4 -10.2969 2424.565
5 -56.6165 3247.935
6 10.7915 2485.77
7 -64.90575 3303.96
8 -27.99575 2657.685
9 -29.57055 3387.125
10 -14.8221 2717.47
11 -42.52235 2368.475
12 -65.28255 3377.95
13 15.37685 2571.02
14 -16.6738 3028.665
15 -49.1765 2486.495
16 -33.0588 3189.775
17 -9.5861 2515.115
18 -39.05465 2322.993
19 -22.12 3119.96
20 -23.77995 2353.378

 



Untitled Post

I'm Online
nlobaugh
Posted on 11/27/13 11:02:31
Number of posts: 229
nlobaugh replies:

If you want to use the gui window, you can click on a brainscore and it will label that subject for all conditions.

Otherwise, it looks like you've pulled out the brainscores from the results, so you could look at the brainscores for taskA in the same way.

n

 



Untitled Post

Posted on 11/27/13 11:24:38
Number of posts:
replies:

I just did this, and there is a positive correlation between brain scores in task A task B (r=0.68). So it looks like the person with the most positive brain score in task A also tends to have the least negative Brain score in Task B. 

And actually, in both tasks A and tasks B, there is a negative correlation between brain scores and RT. 

So to summarize:

- I did a non-rotated PLS, which gives a significant LV in which positive saliences are more active in Task a vs. B and negative saliences are more activae in Task B vs. A.
- I extracted brain scores from both tasks A and B
- Brain scores for Task A are negatively correlated with RT in task A.
- Brain scores for Task B are negatively correlated with RT in task B
- Brain scores in Task A are positively correlated with brain scores in task B.

So for the interpretation: I would say that 

- More activation in positive salience regions in Task A were related to faster responding
- But my confusion is for  Task B. Can I interpret the negative correlation between brain scores and RT in the same way as for task A? In other words, is the interpretation of a negative correlation between brain score and RT the same for positive saliences and negative saliences, or should the interpretation be flipped? Was greater activation in negative salience regions in task B associated with faster or longer RT? 

Thanks, and sorry for all these messages!

David




Login to reply to this topic.

  • Keep in touch

Enter your email above to receive electronic messages from Baycrest, including invitations to programs and events, newsletters, updates and other communications.
You can unsubscribe at any time.
Please refer to our Privacy Policy or contact us for more details.

  • Follow us on social
  • Facebook
  • Instagram
  • Linkedin
  • Pinterest
  • Twitter
  • YouTube

Contact Us:

3560 Bathurst Street
Toronto, Ontario
Canada M6A 2E1
Phone: (416) 785-2500

Baycrest is an academic health sciences centre fully affiliated with the University of Toronto